All networks are available as gzipped, tab-delimited text files. The file format is as follows:
Top Edges: the network is filtered to only include edges with evidence supporting a tissue-specific functional interaction [entrez gene id 1][entrez gene id 2][posterior prob.] Full Network: the network is fully connected [entrez gene id 1][entrez gene id 2][posterior prob., with known edges set to 1][posterior prob.] Gold Standard: each file (e.g. kidney.dab.tar.gz) when decompressed results in a DAB file that contains edges with values 1 through 4 corresponding to C1 - C4 described in our paper. C1 edges are used as positives and C2-C4 are used as negatives to train the tissue-specific models.
Note: These downloadable networks assume a prior probability of 0.1 to match the displayed networks
Tissue | Top Edges | Full Network | Gold Standard |
dentate gyrus | dentate_gyrus_top.gz | dentate_gyrus.gz | dentate_gyrus.dat.tar.gz |
entorhinal cortex | entorhinal_cortex_top.gz | entorhinal_cortex.gz | entorhinal_cortex.dat.tar.gz |
hippocampus CA1 | hippocampus_CA1_top.gz | hippocampus_CA1.gz | hippocampus_CA1.dat.tar.gz |
hippocampus CA2 | hippocampus_CA2_top.gz | hippocampus_CA2.gz | hippocampus_CA2.dat.tar.gz |
hippocampus CA3 | hippocampus_CA3_top.gz | hippocampus_CA3.gz | hippocampus_CA3.dat.tar.gz |
primary somatosensory cortex | primary_somatosensory_cortex_top.gz | primary_somatosensory_cortex.gz | primary_somatosensory_cortex.dat.tar.gz |
visual cortex | visual_cortex_top.gz | visual_cortex.gz | visual_cortex.dat.tar.gz |